RUDOLPH LABORATORY

Excited About Inhibition

PUBLICATIONS

Full list can be found here >

2024

Niepoth N, Merritt JR, Uminski M, Lei E, Esquibies VS, Bando IB, Hernandez K, Gebhardt C, Wacker SA, Lutzu S, Poudel A, Soma KK, Rudolph S, Bendesky A. Evolution of a novel adrenal cell type that promotes parental care. Nature. 2024 May 15. doi: 10.1038/s41586-024-07423-y. Epub ahead of print. PMID: 38750354.

Hyde RJ, Rudolph S. More than meets the eye: A conserved sensorimotor reflex helps unravel the circuit mechanisms of ASD. Neuron. 2024 May 1;112(9):1375-1378. doi: 10.1016/j.neuron.2024.04.003. PMID: 38697019. 

2023

Rudolph S, Badura A, Lutzu S, Pathak SS, Thieme A, Verpeut JL, Wagner MJ, Yang YM, Fioravante D. Cognitive-Affective Functions of the Cerebellum. J Neurosci. 2023 Nov 8;43(45):7554-7564. doi: 10.1523/JNEUROSCI.1451-23.2023. PMID: 37940582; PMCID: PMC10634583.

2022

Osorno T*, Rudolph S*, Nguyen T, Kozareva V, Nadaf NM, Norton A, Macosko EZ, Lee WA, Regehr WG. Candelabrum cells are ubiquitous cerebellar cortex interneurons with specialized circuit properties. Nat Neurosci. 2022 May 16. doi: 10.1038/s41593-022-01057-x. *equal contribution

2021

Kozareva V, Martin C, Osorno T, Rudolph S, Guo C, Vanderburg C, Nadaf N, Regev A, Regehr WG, Macosko E. A transcriptomic atlas of mouse cerebellar cortex comprehensively defines cell types. Nature. 2021 Oct;598(7879):214-219. doi: 10.1038/s41586-021-03220-z. Epub 2021 Oct 6.

Osorno T*, Rudolph S*, Nguyen T, Kozareva V, Nadaf N,
 Macosko EZ, Lee WC, Regehr WG *equal contribution
Candelabrum cells are molecularly distinct, ubiquitous interneurons of the cerebellar cortex with specialized circuit properties
BioRxiv

Guo C, Rudolph S, Neuwirth ME, Regehr WG
Purkinje cell outputs selectively inhibit a subset of unipolar brush cells in the input layer of the cerebellar cortex
Elife. 2021 Aug 9;10:e68802. doi: 10.7554/eLife.68802

Yap EL, Pettit NL, Davis CP, Nagy MA, Harmin DA, Golden E, Dagliyan O, Lin C, Rudolph S, Sharma N, Griffith EC, Harvey CD, Greenberg ME
Bidirectional perisomatic inhibitory plasticity of a Fos neuronal network
Nature, 2021 Feb;590(7844):115-121.

2020

Rudolph S, Guo C, Pashkovski S, Osorno T, Gillis W, Krauss JM, Nyitrai H, Flaquer I, El-Rifai M, Datta RS, Regehr WG
Cerebellum-Specific Deletion of the GABAA Receptor δ Subunit Leads to Sex-Specific Disruption of Behavior
Cell Reports. 2020 Nov 3;33(5):108338.

Kozareva V, Martin C, Osorno T, Rudolph S, Guo C, Vanderburg C, Nadaf N, Regev A, Regehr WG, Macosko E
A transcriptomic atlas of the mouse cerebellum reveals regional specializations and novel cell types
BioRxiv

2019

Pieper A*, Rudolph S*, Wieser GL, Götze T, Mießner H, Yonemasu T, Yan K, Tzvetanova I, Duverge Castillo B, Bode U, Bormuth I, Wadiche JI, Schwab MH, Goebbels S. *equal contribution
NeuroD2 controls inhibitory circuitry formation in the molecular layer of the cerebellum.
Science Reports. 2019 Feb 5;9(1):1448

2018

Tsai PT, Rudolph S, Guo C, Ellegood J, Gibson JM, Schaeffer SM, Mogavero J, Lerch JP, Regehr WG, Sahin M.
Sensitive Periods for Cerebellar Mediated Autistic-like Behaviors.
Cell Reports. 2018; 25(2), 357-367.e4

2017

Tang JC, Rudolph S, Cepko CL.
Viral Delivery of GFP-Dependent Recombinases to the Mouse Brain.
Methods Mol Biol. 2017; 1642:109-126. PMID: 28815497

2016

Tang JC, Drokhlyansky E, Etemad B, Rudolph S, Guo B, Wang S, Ellis EG, Li JZ, Cepko CL.

Detection and manipulation of live antigen-expressing cells using conditionally stable nanobodies.
Elife, 2016 May 20;5. pii: e15312.

Witter L*, Rudolph S*, Pressler RT, Lahlaf SI, Regehr WG.
*equal contribution
Purkinje Cell Collaterals Enable Output Signals from the Cerebellar Cortex to Feed Back to Purkinje Cells and Interneurons.
Neuron, 2016 Jul 20;91(2):312-9.

Guo C, Witter L, Rudolph S, Elliott HL, Ennis KA, Regehr WG.
Purkinje Cells Directly Inhibit Granule Cells in Specialized Regions of the Cerebellar Cortex.
Neuron, 2016 Sep 21;91(6):1330-41.

2015

Rudolph S., Thanawala M.
Location matters: Somatic and dendritic SK channels answer to distinct calcium signals.
Journal of Neurophysiology, 2015, 2015 Jul;114(1):1-5

Rudolph S, Hull C, Regehr WG.
Active Dendrites and Differential Distribution of Calcium Channels Enable Functional Compartmentalization of Golgi Cells.
Journal of Neuroscience, 2015, 35(47):15492-504.

Tang JC, Rudolph S, Dhande OS, Abraira VE, Choi S, Lapan SW, Drew IR, Drokhlyansky E, Huberman AD, Regehr WG, Cepko CL.
Cell type-specific manipulation with GFP-dependent Cre recombinase.
Nature Neuroscience, 2015, 18(9):1334-41.

earlier

Coddington LT, Rudolph S, Vande Lune P, Overstreet-Wadiche L, Wadiche JI
Spillover Activation of Inhibition Segregates Interneuronal Subpopulations in the Cerebellar Cortex.
Neuron. 2013, 78(6):1050-62.

Leuner K, Li W, Amaral MD, Rudolph S, Calfa G, Schuwald AM, Harteneck C, Inoue T, Pozzo-Miller L.
Hyperforin modulates dendritic spine morphology in hippocampal pyramidal neurons by activating Ca(2+) -permeable TRPC6 channels.
Hippocampus. 2012, 23(1):40-52

Rudolph S, Overstreet-Wadiche L, Wadiche JI,
Desynchronization of multivesicular release enhances Purkinje cell output.
Neuron. 2011, 70(5):991-1004

Nadrigny F, Li D, Kemnitz K, Ropert N, Koulakoff A, Rudolph S, Vitali M, Giaume C, Kirchhoff F, Oheim M.
Systematic colocalization errors between acridine orange and EGFP in astrocyte vesicular organelles.
Biophysical Journal. 2007; 93(3):969-80.